Sinonasal disease, especially rhinosinusitis, is the most prevalent disease in the Otorhinolaryngology-Head and Neck Surgery Department. Different anatomical variations of the lateral walls of the nose play an important role in contributing to osteomeatal complex obstruction and drainage and ventilation distruption, which eventually causes
inflammation of the sinus mucosa. To discover the characteristics of sinonasal anatomical variations in patients with chronic rhinosinusitis based on their CT scan findings. This is an observative descriptive study using a cross-sectional design. All chronic rhinosinusitis patients who came to Otorhinolaryngology in H Adam Malik General Hospital and Universitas Sumatera Utara Hospital, Medan, Indonesia, will undergo CT Scan examination to explore their anatomical variation. This study’s inclusion criteria are a patient diagnosed with chronic rhinosinusitis, which is not diagnosed with a nasal polyp, who does not have a history of nasal trauma and has no history of previous nasal surgery. Of 40 patients with chronic rhinosinusitis, 21 patients were male, and 19 patients were female. The most prevalent anatomical variation found is a septal deviation (18 patients/ 45%), with maxillary sinus as the most involved sinus (85%). From the CT scan findings of chronic rhinosinusitis patients, the most prevalent anatomical variation is a septal deviation found in 18 patients (45%). This high incidence of anatomical variation needs proper preoperative assessment for safe and effective endoscopic sinus surgery.

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