Early diagnosis of jaw pathologies in patients with CP and evaluation of the effectiveness of timely treatment. Comprehensive anthropometric, dental, laboratory, and sociological studies were conducted on 299 children and adolescents aged 6 to 18 years, including 143 with CP (main group – MG) and 156 somatically healthy (control group – CG) who required dental care. Treatment and prevention of dental system pathologies, malocclusion defects and preliminary prediction of existing pathology risks, along with the developed treatment regimen, lead to high effectiveness of prevention of dental system abnormalities. This research is very relevant in the field of dentistry, maxillofacial surgery, and prosthetics. And, in speech therapy and psychology, since by treating dentition, we give children a beautiful smile, even teeth, which directly affects diction. Novelty/originality of this study: for the first time in Uzbekistan, we studied the prevalence of dental morbidity, malocclusion and periodontal diseases among children aged 6-18 years. We also assessed the biochemical status of the oral cavity for the first time by studying the microbiome of saliva during prosthetics made of different materials.

1. J.-L. Sixou, N. Vernusset, A. Daigneau, D. Watine, and L. Marin, “Orofacial therapy in infants with down syndrome,” Journal of Dentofacial Anomalies and Orthodontics, vol. 20, no. 1, p. 108, 2017.
2. J. M. Felcar, I. R. Bueno, A. C. S. Massan, R. P. Torezan, and J. R. Cardoso, “Prevalence of mouth breathing in children from an elementary school,” Ciencia & saude coletiva, vol. 15, no. 2, p. 427, 2010.
3. J.-M. Landouzy, A. S. Delattre, R. Fenart, B. Delattre, J. Claire, and M. Biecq, “La langue: déglutition, fonctions oro-faciales, croissance crânio-faciale,” International Orthodontics, vol. 7, no. 3, pp. 227–256, 2009.
4. E. S. Bimbas, A. S. Shishmareva, and M. A. Melnikova, “Facial skeleton development in children after early loss of temporary upper jaw incisors,” Problems of dentistry, no. 3, pp. 96–99, 2017.
5. S. A. Gafforov, N. S. Madaminova et al., “Analysis of modern literature data on the improvement of the clinic, treatment, diagnosis and prognosis of dental pathologies in children and adolescents with cerebral palsy.” Journal of Pharmaceutical Negative Results, vol. 13, 2022.
6. S. A. Gafforov, F. S. Hamroev, V. B. Kuldasheva, M. O. Shamsiyeva, N. S. Madaminova et al., “Clinical condition of teeth and dentition in children and adolescents with cerebral palsy,” Russian Journal of Dentistry, vol. 26, no. 5, pp. 371–379, 2022.
7. H. Al Hashmi, M. Kowash, A. Hassan, and M. Al Halabi, “Oral health status among children with cerebral palsy in dubai, united arab emirates,” Journal of International Society of Preventive and Community Dentistry, vol. 7, no. Suppl 3, pp. S149–S154, 2017.
8. E. M. McBride, R. J. Lawrence, K. McGee, P. M. Mach, P. S. Demond, M. W. Busch, J. W. Ramsay, E. K. Hussey, T. Glaros, and E. S. Dhummakupt, “Rapid liquid chromatography tandem mass spectrometry method for targeted quantitation of human performance metabolites in saliva,” Journal of Chromatography A, vol. 1601, pp. 205–213, 2019.
9. E. Pokrovskaya, S. Khaliullina, V. Anokhin, K. Khaliullina, K. S. Khaertinov, V. Krasnozhen, and K. S. Viktorovna, “Optimization of treatment of lymphopharyngeal ring organ hypertrophy in children infected with herpes viruses,” Pract. Med, vol. 18, no. 6, 2020.
10. N. Madaminova and M. Shamsieva, “Anthropometric characteristics of the skull bones and deformities of the dentofacial system in children and adolescents with cerebral palsy.”
11. S. Gafforov and G. Fazilbekova, “A scientific view of the problem of treatment and prevention of dental anomaly in children with diseases of bronchial asthma,” ISJ Theoretical & Applied Science, 07 (87), pp. 424–431, 2020.
12. S. Gafforov, F. Khamroev, M. Shamsieva, and N. Madaminova, “Anthropometric and clinicaldental condition of the maxillary system and oral organs in patients with cerebral palsy,” AGRICULTURAL SCIENCES, p. 32, 2023.
13. M. I.-G. Al, I. Fotopoulos, and L. Zouloumis, “Dental management of patients with autism spectrum disorders,” Balkan Journal of Dental Medicine, vol. 19, no. 3, pp. 124–127, 2015.

N. S. Madaminova, S. A. Gafforov and F. S. Khamroyev, “Diagnosis and Treatment of Jaws and Oral Organs in Patients with Splastic Cerebral Palsy”, International Journal of Health and Medical Sciences, vol. 10, pp.29-33, 2024. Doi: https://dx.doi.org/10.20469/ijhms.10.30004