One myth about entrepreneurship is that an entrepreneur was born, not made. Even that is a myth, but many people still believe the myth is true. This research aims to reveal what learning method of entrepreneurship and innovation can effectively increase, motivate the student is entrepreneurial, increase the skill of entrepreneurship, the spirit of an entrepreneur and entrepreneurial intentions. Data from the 73 students were collected through a questionnaire. The result from 73 students of entrepreneurship and innovation revealed that learning method entrepreneurship project and sales session could increase the skill, motivation, and spirit of entrepreneurship, and 64.1% interest be an entrepreneur and 67% want to learn more about entrepreneurship. The findings suggest increasing the motivation of entrepreneurship student’s, give the best rank for entrepreneurship project, presenting the project, sales session and knowing other countries culture. Learning method can increase the spirit of entrepreneurship from the students’ perspective are entrepreneur project, lecture, sales session and presentation of the project.

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