UV-Visible Spectrophotometer Analysis on Polymerization of 2-Hydroxyethyl Methacrylate
Volume 3, Issue 2 MUHD. HAZWAN HAKIM HISHAM, AZHAR ABDUL RAHMAN, ISKANDAR SHAHRIM MUSTAFA
Published online:14 July 2017
Article Views: 38
Abstract
Polymer gel has been used as a dosimeter to determine spatial dose distributions by radiotherapy equipment. This study explores the absorption peak in the UV-visible (UV-vis) spectrophotometer as the relative intensity of polymerization. Theoretically, high intensity of polymerization results in high absorbance. The size of gold nanoparticles (GNPs) and dose of irradiation are expected to affect polymerization. Normoxic polymer gel samples using 2-Hydroxyethyl methacrylate (HEMA) as the monomer were prepared with different sizes of GNPs to study the effect of GNPs with ascorbic acid acting as the oxygen scavenger. Linear accelerator (LINAC) was the source of high irradiation x-ray energy as it is one of the most widely used radiotherapy equipment. The diagnostic x-ray unit acted as a low energy source. One crucial factor in fabricating the sample is the environment temperature. Radiation-induced polymer gel is environmentally sensitive where a low-temperature environment (<5◦C) is needed to ensure the structural stability of the gel. The UV-vis analysis shows that the absorbance increases when the irradiation doses increase, while the size of GNPs affects the absorbance value depending on the irradiation dose.
Reference
M. Oldham, I. Baustert, C. Lord, T. Smith, M. McJury, A. Warrington, M. Leach and S. Webb, “An investigation into the dosimetry of a nine-field tomotherapy irradiation using BANG-gel dosimetry,” Journal of Physics in Medicine and Biology, vol. 43, no. 5, pp. 1113-1132, 1998. https://doi.org/10.1088/0031-9155/43/5/005 PMid:9623644
D. A. Low, J. F. Dempsey, R. Venkatesan, S. Mutic, J. Markman, E. M. Haacke and J. A. Purdy, “Evaluation of polymer gels and MRI as a 3-D dosimeter for intensity-modulated radiation therapy,”Medical Physics, vol. 26, no. 8, pp. 1542-1551, 1999. https://doi.org/10.1118/1.598650 PMid:10501054
M. Pfaender, G. Grebe, V. Budach, and R. Wurm, “Dosimetry with Bang-dosimeters regarding slim shaped parts of lesions for stereotactic radiation with a linac and micro-multi-leaf-collimator,” in Proceedings of the 1st International Workshop on Radiation Gel Dosimetry, pp. 190192, 1999.
P. Alexander and M. Fox, “The degradation of polymethacrylic acid by X-rays,” Transactions of the Faraday Society, vol. 50, pp. 605-612, 1954. https://doi.org/10.1039/tf9545000605
P. Y. Feng, “Polymer degradation: Wide range dosimeter,” Nucleonics, vol. 16, no. 10, p. 114.
M. J. Maryanski, J. C. Gore, R. P. Kennan and R. J. Schulz, “NMR relaxation enhancement in gels polymerized and cross-linked by ionizing radiation: A new approach to 3D dosimetry by MRI,” Magnetic Resonance Imaging, vol. 11, no. 2, pp. 253-258, 1993. https://doi.org/10.1016/0730-725X(93)90030-H
R. Narakhetudomsak and T. Tondee, “Rapid chemical oxygen demand analysis by total organic carbon correlation,” International Journal of Applied and Physical Sciences, vol. 2, no. 1, pp. 1-6, 2016.
P.M. Fong, D. C. Keil, M. D. Does and J. C. Gore, “Polymer gels for magnetic resonance imaging of radiation dose distributions at normal room atmosphere,” Journal of Physics in Medicine and Biology, vol. 46, no. 12, pp. 3105-3113, 2001. https://doi.org/10.1088/0031-9155/46/12/303 PMid:11768494
M. A. CheYunus, M. S. H. Ruslan, J. B. Jamal, W. A. W. Abdul Aziz and Z. BintiIdham, “Extraction of beta-carotene from palm mesocarp via green sub-criticae Carbon Dioxide,” Journal of Advances in Technology and Engineering Research, vol. 1, no. 1, pp. 15-21, 2015.
J. F. Hainfeld, H. M. Smilowitz, M. J. O’Connor, F. A. Dilmanian and D. N. Slatkin, “Gold nanoparticle imaging and radiotherapy of brain tumors in mice,” Nano Medicine, vol. 8, no. 10, pp. 1601-1609, 2013. https://doi.org/10.2217/nnm.12.165 PMid:23265347 PMCid:PMC3657324
To Cite this article
M. H. H. Hisham, A. A. Rahman and I. S. Mustafa,“UV-visible spectrophotometer analysis on polymerization of 2-hydroxyethyl methacrylate,” International Journal of Applied and Physical Sciences, vol. 3, no. 2, pp. 42-45, 2017.