This study was conducted to verify the effects of a mentoring program on college life adaptability and learning attitude of nursing students. Data was collected from college students who participated in senior-junior mentoring activity from March to June, 2018. The data from 233 students was processed to evaluate the effects of senior-junior mentoring program by single research. College life satisfaction and learning Attitude were used as research tools and the collected data was processed by SPSS Win 18.0 program with descriptive statistics such as real numbers, percentage, average and standard deviation. The differences of variables according to general characteristics were implemented by t-test, ANOVA and Scheffe test was used for post-verification. The relationship among the variables was handled by Pearson correlation. In this study, the higher grades students were in and the longer they took part in the mentoring activity, the more significantly their college life adaptability increased. The numbers of participation, advice and motivation were also significant. In addition, the longer they attended the research, the better their learning attitude became. The numbers of participation, advice and motivation were also significant. A mentoring program is regarded to have a significant effect on college life adaptation and learning attitude of nursing students. The mentoring relationship among nursing students appears to build up positive effects on their major adaptation and learning attitude. When nursing departments make good use of a mentoring activity based on these results, it is seen to give the students positive help with college life.

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