Juvenile Nasopharyngeal Angiofibroma (JNA) is a benign blood vessel tumor locally aggressive in young adults. VEGF is an important growth factor in tumor biology. VEGF overexpression has been associated with tumor progression and poor prognosis in various types of tumors. VEGF expression in angiofibroma has been previously noted and associated with proliferation and increasing blood vessel density. To determine the Vascular Endothelial Growth Factor (VEexpression GF) in JNA, descriptive research with a cross-sectional study design was taken from medical records at the H. Adam Malik general hospital Medan from January 2011 to December 2ith a total sample of 24. Inclusion criteria included a sticky medical record and cleared identify and had paraffin blocks with a JNA diagnosis. VEGF overexpression was found in 14 male patients (60.9%) and 11 people (61.1%) of 18 people under the age of 20. In stage III, VEGF overexpression was found to be 90%, and at stage IV reached 100%. VEGF overexpression in JNA was found especially at advanced stages.

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Sari, Y. T., Asnir, R. A., Yudhistira, A., & Elliandy, S. (2018). Expression of Vascular Endothelial Growth Factor (VEGF) in juvenile nasopharyngeal angiofibroma in Haji Adam Malik General Hospital Medan. International Journal of Health and Medical Sciences, 4(3), 72–76. doi:https://doi.org/10.20469/ijhms.40003-3